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Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain

The ventrobasal (VB) thalamus is innervated by GABAergic afferents from the thalamic reticular nucleus (TRN) and participates in nociception. But how the TRN-VB pathway regulates pain is not fully understood. In the present study, we reported decreased extracellular GABA levels in the VB of rats wit...

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Detalles Bibliográficos
Autores principales: Zhang, Chan, Chen, Rong-Xiang, Zhang, Yu, Wang, Jie, Liu, Feng-Yu, Cai, Jie, Liao, Fei-Fei, Xu, Fu-Qiang, Yi, Ming, Wan, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288727/
https://www.ncbi.nlm.nih.gov/pubmed/28150719
http://dx.doi.org/10.1038/srep41439