Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/NF-κB inactivation

Constitutive NF-E2-related factor 2 (Nrf2, NFE2L2) activation has been recently reported to play a pivotal role in enhancing cell survival and resistance to anticancer drugs in many tumors. Wogonin had strong reversal potency via reduction of Nrf2 mRNA in Adriamycin (ADR)-induced resistant human chr...

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Detalles Bibliográficos
Autores principales: Xu, Xuefen, Zhang, Xiaobo, Zhang, Yi, Yang, Lin, Liu, Yicheng, Huang, Shaoliang, Lu, Lu, Kong, Lingyi, Li, Zhiyu, Guo, Qinglong, Zhao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288730/
https://www.ncbi.nlm.nih.gov/pubmed/28150717
http://dx.doi.org/10.1038/srep39950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288730/
https://www.ncbi.nlm.nih.gov/pubmed/28150717
http://dx.doi.org/10.1038/srep39950

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