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Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies

The interaction of a small library of cyclic DKP–RGD peptidomimetics with α(5)β(1) integrin has been investigated by means of an integrated experimental and computational approach. Bioaffinity NMR techniques, including saturation transfer difference (STD) and transferred NOESY, were applied to the l...

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Detalles Bibliográficos
Autores principales: Guzzetti, Ileana, Civera, Monica, Vasile, Francesca, Arosio, Daniela, Tringali, Cristina, Piarulli, Umberto, Gennari, Cesare, Pignataro, Luca, Belvisi, Laura, Potenza, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288746/
https://www.ncbi.nlm.nih.gov/pubmed/28168158
http://dx.doi.org/10.1002/open.201600112