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Levofloxacin loaded mesoporous silica microspheres/nano-hydroxyapatite/polyurethane composite scaffold for the treatment of chronic osteomyelitis with bone defects

Chronic osteomyelitis is a prolonged persistent disease accompanied by bone destruction and sequestrum formation, it is very difficult to treat. Antibiotic loaded polymethyl methacrylate (PMMA) has been used in clinical. However, when PMMA was implanted in the body, the deficiencies is that it is no...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Chen, Cheng, Liu, Wen, He, Xiaoqiang, Zhou, Nian, Zhang, Dongli, Gu, Hongchen, Li, Jidong, Jiang, Jiaxing, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288772/
https://www.ncbi.nlm.nih.gov/pubmed/28150731
http://dx.doi.org/10.1038/srep41808