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Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

SRY, a sex-determining gene, induces testis development in chromosomally female (XX) individuals. However, mouse XX Sertoli cells carrying Sry (XX/Sry Sertoli cells) are incapable of fully supporting germ cell development, even when the karyotype of the germ cells is XY. While it has therefore been...

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Detalles Bibliográficos
Autores principales: Shishido, Yurina, Baba, Takashi, Sato, Tetsuya, Shima, Yuichi, Miyabayashi, Kanako, Inoue, Miki, Akiyama, Haruhiko, Kimura, Hiroshi, Kanai, Yoshiakira, Ishihara, Yasuhiro, Haraguchi, Shogo, Miyazaki, Akira, Rozman, Damjana, Yamazaki, Takeshi, Choi, Man-Ho, Ohkawa, Yasuyuki, Suyama, Mikita, Morohashi, Ken-ichirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288785/
https://www.ncbi.nlm.nih.gov/pubmed/28150810
http://dx.doi.org/10.1038/srep41912