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Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans

Decellularization of pancreata and repopulation of these non-immunogenic matrices with islets and endothelial cells could provide transplantable, endocrine Neo- Pancreata. In this study, rat pancreata were perfusion decellularized and repopulated with intact islets, comparing three perfusion routes...

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Detalles Bibliográficos
Autores principales: Napierala, H., Hillebrandt, K.-H., Haep, N., Tang, P., Tintemann, M., Gassner, J., Noesser, M., Everwien, H., Seiffert, N., Kluge, M., Teegen, E., Polenz, D., Lippert, S., Geisel, D., Reutzel Selke, A., Raschzok, N., Andreou, A., Pratschke, J., Sauer, I. M., Struecker, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288794/
https://www.ncbi.nlm.nih.gov/pubmed/28150744
http://dx.doi.org/10.1038/srep41777