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Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging
BACKGROUND: There is a growing interest in simple molecular biomarkers for biological aging. Age-associated DNA methylation (DNAm) changes at specific CG dinucleotides can be combined into epigenetic age predictors to estimate chronological age—and the deviation of chronological and predicted age (∆...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288846/ https://www.ncbi.nlm.nih.gov/pubmed/28168006 http://dx.doi.org/10.1186/s13148-017-0315-9 |