Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging

BACKGROUND: There is a growing interest in simple molecular biomarkers for biological aging. Age-associated DNA methylation (DNAm) changes at specific CG dinucleotides can be combined into epigenetic age predictors to estimate chronological age—and the deviation of chronological and predicted age (∆...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yan, Hapala, Jan, Brenner, Hermann, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288846/
https://www.ncbi.nlm.nih.gov/pubmed/28168006
http://dx.doi.org/10.1186/s13148-017-0315-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288846/
https://www.ncbi.nlm.nih.gov/pubmed/28168006
http://dx.doi.org/10.1186/s13148-017-0315-9

Ejemplares similares