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Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging

BACKGROUND: There is a growing interest in simple molecular biomarkers for biological aging. Age-associated DNA methylation (DNAm) changes at specific CG dinucleotides can be combined into epigenetic age predictors to estimate chronological age—and the deviation of chronological and predicted age (∆...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, Hapala, Jan, Brenner, Hermann, Wagner, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288846/ https://www.ncbi.nlm.nih.gov/pubmed/28168006 http://dx.doi.org/10.1186/s13148-017-0315-9

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