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A novel statistical approach for identification of the master regulator transcription factor
BACKGROUND: Transcription factors are known to play key roles in carcinogenesis and therefore, are gaining popularity as potential therapeutic targets in drug development. A ‘master regulator’ transcription factor often appears to control most of the regulatory activities of the other transcription...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288875/ https://www.ncbi.nlm.nih.gov/pubmed/28148240 http://dx.doi.org/10.1186/s12859-017-1499-x |