Cargando…

TBK1: a new player in ALS linking autophagy and neuroinflammation

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder affecting motor neurons, resulting in progressive muscle weakness and death by respiratory failure. Protein and RNA aggregates are a hallmark of ALS pathology and are thought to contribute to ALS by impairing axonal tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Oakes, James A., Davies, Maria C., Collins, Mark O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288885/
https://www.ncbi.nlm.nih.gov/pubmed/28148298
http://dx.doi.org/10.1186/s13041-017-0287-x