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Meiotic outcome in two carriers of Y autosome reciprocal translocations: selective elimination of certain segregants

BACKGROUND: Reciprocal Y autosome translocations are rare but frequently associated with male infertility. We report on the meiotic outcome in embryos fathered by two males with the karyotypes 46,X,t(Y;4)(q12;p15.32) and 46,X,t(Y;16)(q12;q13). The two couples underwent preimplantation genetic diagno...

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Detalles Bibliográficos
Autores principales: Ghevaria, Harita, Naja, Roy, SenGupta, Sioban, Serhal, Paul, Delhanty, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289000/
https://www.ncbi.nlm.nih.gov/pubmed/28184250
http://dx.doi.org/10.1186/s13039-017-0303-y