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DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles

BACKGROUND: T cell receptor (TCR) molecules are involved in the adaptive immune response as they distinguish between self- and foreign-peptides, presented in major histocompatibility complex molecules (pMHC). Former studies showed that the association angles of the TCR variable domains (Vα/Vβ) can d...

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Detalles Bibliográficos
Autores principales: Hoffmann, Thomas, Marion, Antoine, Antes, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289058/
https://www.ncbi.nlm.nih.gov/pubmed/28148269
http://dx.doi.org/10.1186/s12900-016-0071-7