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DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles
BACKGROUND: T cell receptor (TCR) molecules are involved in the adaptive immune response as they distinguish between self- and foreign-peptides, presented in major histocompatibility complex molecules (pMHC). Former studies showed that the association angles of the TCR variable domains (Vα/Vβ) can d...
Autores principales: | Hoffmann, Thomas, Marion, Antoine, Antes, Iris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289058/ https://www.ncbi.nlm.nih.gov/pubmed/28148269 http://dx.doi.org/10.1186/s12900-016-0071-7 |
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