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Slowdown of growth controls cellular differentiation

How can changes in growth rate affect the regulatory networks behavior and the outcomes of cellular differentiation? We address this question by focusing on starvation response in sporulating Bacillus subtilis. We show that the activity of sporulation master regulator Spo0A increases with decreasing...

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Detalles Bibliográficos
Autores principales: Narula, Jatin, Kuchina, Anna, Zhang, Fang, Fujita, Masaya, Süel, Gürol M, Igoshin, Oleg A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289222/
https://www.ncbi.nlm.nih.gov/pubmed/27216630
http://dx.doi.org/10.15252/msb.20156691