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Chemogenomics and orthology‐based design of antibiotic combination therapies

Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification of effective combinations highly challenging. Here, we present a computational app...

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Detalles Bibliográficos
Autores principales: Chandrasekaran, Sriram, Cokol‐Cakmak, Melike, Sahin, Nil, Yilancioglu, Kaan, Kazan, Hilal, Collins, James J, Cokol, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289223/
https://www.ncbi.nlm.nih.gov/pubmed/27222539
http://dx.doi.org/10.15252/msb.20156777