CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene

The cellular isoform of the prion protein (PrP(C)) plays critical roles in the development of prion disorders. Although PrP mRNA is ubiquitously present in a tissue-specific manner, the DNA methylation of PrP gene (Prnp) is still unknown. In this study, we demonstrated that the CpG island (CGI, posi...

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Detalles Bibliográficos
Autores principales: DALAI, Wuyun, MATSUO, Eiko, TAKEYAMA, Natsumi, KAWANO, Junichi, SAEKI, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2016
Materias:
Virology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289245/
https://www.ncbi.nlm.nih.gov/pubmed/27666463
http://dx.doi.org/10.1292/jvms.16-0390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289245/
https://www.ncbi.nlm.nih.gov/pubmed/27666463
http://dx.doi.org/10.1292/jvms.16-0390

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