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Kinetic characteristics of chimeric channelrhodopsins implicate the molecular identity involved in desensitization

Channelrhodopsin (ChR)-1 and ChR2 were the first-identified members of ChRs which are a growing subfamily of microbial-type rhodopsins. Light absorption drives the generation of a photocurrent in cell membranes expressing ChR2. However, the photocurrent amplitude attenuates and becomes steady-state...

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Detalles Bibliográficos
Autores principales: Zamani, Alemeh, Sakuragi, Shigeo, Ishizuka, Toru, Yawo, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289414/
https://www.ncbi.nlm.nih.gov/pubmed/28409086
http://dx.doi.org/10.2142/biophysico.14.0_13