Identification of small molecules that disrupt vacuolar function in the pathogen Candida albicans

The fungal vacuole is a large acidified organelle that performs a variety of cellular functions. At least a sub-set of these functions are crucial for pathogenic species of fungi, such as Candida albicans, to survive within and invade mammalian tissue as mutants with severe defects in vacuolar bioge...

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Detalles Bibliográficos
Autores principales: Tournu, Helene, Carroll, Jennifer, Latimer, Brian, Dragoi, Ana-Maria, Dykes, Samantha, Cardelli, James, Peters, Tracy L., Eberle, Karen E., Palmer, Glen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289544/
https://www.ncbi.nlm.nih.gov/pubmed/28151949
http://dx.doi.org/10.1371/journal.pone.0171145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289544/
https://www.ncbi.nlm.nih.gov/pubmed/28151949
http://dx.doi.org/10.1371/journal.pone.0171145

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