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Contextual Refinement of Regulatory Targets Reveals Effects on Breast Cancer Prognosis of the Regulome

Gene expression regulators, such as transcription factors (TFs) and microRNAs (miRNAs), have varying regulatory targets based on the tissue and physiological state (context) within which they are expressed. While the emergence of regulator-characterizing experiments has inferred the target genes of...

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Detalles Bibliográficos
Autores principales: Andrews, Erik, Wang, Yue, Xia, Tian, Cheng, Wenqing, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289608/
https://www.ncbi.nlm.nih.gov/pubmed/28103241
http://dx.doi.org/10.1371/journal.pcbi.1005340