Protein Phosphatase 1 Down Regulates ZYG-1 Levels to Limit Centriole Duplication

In humans perturbations of centriole number are associated with tumorigenesis and microcephaly, therefore appropriate regulation of centriole duplication is critical. The C. elegans homolog of Plk4, ZYG-1, is required for centriole duplication, but our understanding of how ZYG-1 levels are regulated...

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Detalles Bibliográficos
Autores principales: Peel, Nina, Iyer, Jyoti, Naik, Anar, Dougherty, Michael P., Decker, Markus, O’Connell, Kevin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289615/
https://www.ncbi.nlm.nih.gov/pubmed/28103229
http://dx.doi.org/10.1371/journal.pgen.1006543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289615/
https://www.ncbi.nlm.nih.gov/pubmed/28103229
http://dx.doi.org/10.1371/journal.pgen.1006543

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