Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

To further resolve the genetic architecture of the inflammatory bowel diseases, ulcerative colitis and Crohn’s disease, we sequenced the whole genomes of 4,280 patients at low coverage, and compared them to 3,652 previously sequenced population controls across 73.5 million variants. We then imputed...

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Detalles Bibliográficos
Autores principales: Luo, Yang, de Lange, Katrina M., Jostins, Luke, Moutsianas, Loukas, Randall, Joshua, Kennedy, Nicholas A., Lamb, Christopher A., McCarthy, Shane, Ahmad, Tariq, Edwards, Cathryn, Serra, Eva Goncalves, Hart, Ailsa, Hawkey, Chris, Mansfield, John C., Mowat, Craig, Newman, William G., Nichols, Sam, Pollard, Martin, Satsangi, Jack, Simmons, Alison, Tremelling, Mark, Uhlig, Holm, Wilson, David C., Lee, James C., Prescott, Natalie J., Lees, Charlie W., Mathew, Christopher G., Parkes, Miles, Barrett, Jeffrey C., Anderson, Carl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289625/
https://www.ncbi.nlm.nih.gov/pubmed/28067910
http://dx.doi.org/10.1038/ng.3761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289625/
https://www.ncbi.nlm.nih.gov/pubmed/28067910
http://dx.doi.org/10.1038/ng.3761

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