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Combined effect of genetic polymorphisms of AURKA and environmental factors on oral cancer development in Taiwan

BACKGROUND: Oral squamous cell carcinoma (OSCC) is the sixth and fourth most common cause of cancer death in men worldwide and in Taiwan, respectively. AURKA, which encodes a centrosome-related serine/threonine kinase, is frequently amplified and overexpressed in many human cancers, particularly adv...

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Detalles Bibliográficos
Autores principales: Chou, Chia-Hsuan, Chou, Ying-Erh, Chuang, Chun-Yi, Yang, Shun-Fa, Lin, Chiao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289639/
https://www.ncbi.nlm.nih.gov/pubmed/28152093
http://dx.doi.org/10.1371/journal.pone.0171583