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HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread

HIV-1 spreads between CD4 T cells most efficiently through virus-induced cell-cell contacts. To test whether this process potentiates viral spread by activating signaling pathways, we developed an approach to analyze the phosphoproteome in infected and uninfected mixed-population T cells using diffe...

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Detalles Bibliográficos
Autores principales: Len, Alice C.L., Starling, Shimona, Shivkumar, Maitreyi, Jolly, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289937/
https://www.ncbi.nlm.nih.gov/pubmed/28122231
http://dx.doi.org/10.1016/j.celrep.2016.12.057