Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion

Mechanical signals from the extracellular matrix (ECM) and cellular geometry regulate the nuclear translocation of transcriptional regulators such as Yes-associated protein (YAP). Elucidating how physical signals control the activity of mechanosensitive proteins poses a technical challenge, because...

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Detalles Bibliográficos
Autores principales: Sero, Julia E., Bakal, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289939/
https://www.ncbi.nlm.nih.gov/pubmed/28065575
http://dx.doi.org/10.1016/j.cels.2016.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289939/
https://www.ncbi.nlm.nih.gov/pubmed/28065575
http://dx.doi.org/10.1016/j.cels.2016.11.015

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