Cargando…

Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation

Tumor-associated lymphatic vessels (LVs) play multiple roles during tumor progression, including promotion of metastasis and regulation of antitumor immune responses by delivering antigen from the tumor bed to draining lymph nodes (LNs). Under steady-state conditions, LN resident lymphatic endotheli...

Descripción completa

Detalles Bibliográficos
Autores principales: Dieterich, Lothar C., Ikenberg, Kristian, Cetintas, Timur, Kapaklikaya, Kübra, Hutmacher, Cornelia, Detmar, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289955/
https://www.ncbi.nlm.nih.gov/pubmed/28217128
http://dx.doi.org/10.3389/fimmu.2017.00066