Cargando…
Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation
Tumor-associated lymphatic vessels (LVs) play multiple roles during tumor progression, including promotion of metastasis and regulation of antitumor immune responses by delivering antigen from the tumor bed to draining lymph nodes (LNs). Under steady-state conditions, LN resident lymphatic endotheli...
Autores principales: | Dieterich, Lothar C., Ikenberg, Kristian, Cetintas, Timur, Kapaklikaya, Kübra, Hutmacher, Cornelia, Detmar, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289955/ https://www.ncbi.nlm.nih.gov/pubmed/28217128 http://dx.doi.org/10.3389/fimmu.2017.00066 |
Ejemplares similares
-
Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability
por: Dieterich, Lothar C., et al.
Publicado: (2019) -
Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis
por: Dieterich, Lothar C., et al.
Publicado: (2020) -
Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread
por: Ma, Qiaoli, et al.
Publicado: (2018) -
Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8(+) T-cell Responses
por: Cousin, Nikola, et al.
Publicado: (2021) -
T Cell Trafficking through Lymphatic Vessels
por: Hunter, Morgan C., et al.
Publicado: (2016)