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Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1

Benzimidazole derivatives of 5,6-dichlorobenzimidazole 1-β-d-ribofuranoside (DRB) comprise the important class of protein kinase CK2 inhibitors. Depending on the structure, benzimidazoles inhibit CK2 with different selectivity and potency. Besides CK2, the compounds can inhibit, with similar activit...

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Detalles Bibliográficos
Autores principales: Kubiński, Konrad, Masłyk, Maciej, Orzeszko, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290066/
https://www.ncbi.nlm.nih.gov/pubmed/27909846
http://dx.doi.org/10.1007/s11010-016-2892-x