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αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin

Upon binding to the extracellular matrix protein, fibronectin, αV-class and α5β1 integrins trigger the recruitment of large protein assemblies and strengthen cell adhesion. Both integrin classes have been functionally specified, however their specific roles in immediate phases of cell attachment rem...

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Detalles Bibliográficos
Autores principales: Bharadwaj, Mitasha, Strohmeyer, Nico, Colo, Georgina P., Helenius, Jonne, Beerenwinkel, Niko, Schiller, Herbert B., Fässler, Reinhard, Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290147/
https://www.ncbi.nlm.nih.gov/pubmed/28128308
http://dx.doi.org/10.1038/ncomms14348