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αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin
Upon binding to the extracellular matrix protein, fibronectin, αV-class and α5β1 integrins trigger the recruitment of large protein assemblies and strengthen cell adhesion. Both integrin classes have been functionally specified, however their specific roles in immediate phases of cell attachment rem...
Autores principales: | Bharadwaj, Mitasha, Strohmeyer, Nico, Colo, Georgina P., Helenius, Jonne, Beerenwinkel, Niko, Schiller, Herbert B., Fässler, Reinhard, Müller, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290147/ https://www.ncbi.nlm.nih.gov/pubmed/28128308 http://dx.doi.org/10.1038/ncomms14348 |
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