A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

Disturbance of endoplasmic reticulum (ER) homoeostasis induces ER stress and leads to activation of the unfolded protein response (UPR), which is an adaptive reaction that promotes cell survival or triggers apoptosis, when homoeostasis is not restored. DDRGK1 is an ER membrane protein and a critical...

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Detalles Bibliográficos
Autores principales: Liu, Jiang, Wang, Ying, Song, Lizhi, Zeng, Linghua, Yi, Weiwei, Liu, Ting, Chen, Huanzhen, Wang, Miao, Ju, Zhenyu, Cong, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290148/
https://www.ncbi.nlm.nih.gov/pubmed/28128204
http://dx.doi.org/10.1038/ncomms14186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290148/
https://www.ncbi.nlm.nih.gov/pubmed/28128204
http://dx.doi.org/10.1038/ncomms14186

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