Cargando…

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

Disturbance of endoplasmic reticulum (ER) homoeostasis induces ER stress and leads to activation of the unfolded protein response (UPR), which is an adaptive reaction that promotes cell survival or triggers apoptosis, when homoeostasis is not restored. DDRGK1 is an ER membrane protein and a critical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jiang, Wang, Ying, Song, Lizhi, Zeng, Linghua, Yi, Weiwei, Liu, Ting, Chen, Huanzhen, Wang, Miao, Ju, Zhenyu, Cong, Yu-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290148/ https://www.ncbi.nlm.nih.gov/pubmed/28128204 http://dx.doi.org/10.1038/ncomms14186

Ejemplares similares

Loss of DDRGK1 impairs IRE1α UFMylation in spondyloepiphyseal dysplasia
por: Yang, Xiao, et al.
Publicado: (2023)

DDRGK1 Regulates NF-κB Activity by Modulating IκBα Stability
por: Xi, Peng, et al.
Publicado: (2013)

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress
por: Grey, Michael J., et al.
Publicado: (2020)

IRE1α is an endogenous substrate of endoplasmic reticulum-associated degradation
por: Sun, Shengyi, et al.
Publicado: (2015)

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
por: Rubio, Claudia, et al.
Publicado: (2011)

Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling
por: Cohen, Nir, et al.
Publicado: (2017)

DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1‐Mediated NRF2 Ubiquitination
por: Wang, Xin, et al.
Publicado: (2023)

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells
por: Cheng, Xiu, et al.
Publicado: (2021)

Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress
por: Zhou, Zhixin, et al.
Publicado: (2022)

IRE1/XBP1 and endoplasmic reticulum signaling — from basic to translational research for cardiovascular disease
por: Fu, Fangyi, et al.
Publicado: (2022)

A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
por: Kimata, Yukio, et al.
Publicado: (2004)

Transdifferentiation mediated tumor suppression by the endoplasmic reticulum stress sensor IRE-1 in C. elegans
por: Levi-Ferber, Mor, et al.
Publicado: (2015)

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases
por: Junjappa, Raghu Patil, et al.
Publicado: (2018)

Probing natural variation of IRE1 expression and endoplasmic reticulum stress responses in Arabidopsis accessions
por: Afrin, Taiaba, et al.
Publicado: (2020)

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
por: Le Thomas, Adrien, et al.
Publicado: (2021)

DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function
por: Cao, Yan, et al.
Publicado: (2021)

Mdm proteins: critical regulators of embryogenesis and homoeostasis
por: Moyer, Sydney M., et al.
Publicado: (2017)

Arabidopsis GAAPs interacting with MAPR3 modulate the IRE1-dependent pathway upon endoplasmic reticulum stress
por: Zhu, Manli, et al.
Publicado: (2019)

Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
por: Promlek, Thanyarat, et al.
Publicado: (2011)

In vitro FRET analysis of IRE1 and BiP association and dissociation upon endoplasmic reticulum stress
por: Kopp, Megan C, et al.
Publicado: (2018)

Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
por: Shemorry, Anna, et al.
Publicado: (2019)

The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1
por: Acosta-Alvear, Diego, et al.
Publicado: (2018)

The ADP-binding kinase region of Ire1 directly contributes to its responsiveness to endoplasmic reticulum stress
por: Le, Quynh Giang, et al.
Publicado: (2021)

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
por: Li, Xia, et al.
Publicado: (2020)

DDRGK1 in urine indicative of tubular cell injury in intensive care patients with serious infections
por: Neziri, Dashurie, et al.
Publicado: (2016)

Hyperoxia induces endoplasmic reticulum stress-associated apoptosis via the IRE1α pathway in rats with bronchopulmonary dysplasia
por: Tong, Xin, et al.
Publicado: (2021)

Apocynin protects endothelial cells from endoplasmic reticulum stress-induced apoptosis via IRE1α engagement
por: Wu, Jie, et al.
Publicado: (2018)

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway
por: Namba, Takushi, et al.
Publicado: (2015)

IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy
por: Shao, Andong, et al.
Publicado: (2022)

Critical roles of nardilysin in the maintenance of body temperature homoeostasis
por: Hiraoka, Yoshinori, et al.
Publicado: (2014)

Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment
por: Banerjee, Aditi, et al.
Publicado: (2016)

Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
por: Sundaram, Arunkumar, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells
por: Márquez, Saioa, et al.
Publicado: (2017)

Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation
por: Riaz, Thoufiqul Alam, et al.
Publicado: (2020)

Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch
por: Krammes, Lena, et al.
Publicado: (2020)

IRE1α and IGF signaling predict resistance to an endoplasmic reticulum stress-inducing drug in glioblastoma cells
por: Rodvold, Jeffrey J., et al.
Publicado: (2020)

The protein kinase Ire1 impacts pathogenicity of Candida albicans by regulating homeostatic adaptation to endoplasmic reticulum stress
por: Sircaik, Shabnam, et al.
Publicado: (2021)

Melatonin Improves Endoplasmic Reticulum Stress-Mediated IRE1α Pathway in Zücker Diabetic Fatty Rat
por: Aouichat, Samira, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation
por: Rodrigues, Bruno Lima, et al.
Publicado: (2022)

Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response
por: Luo, Ruixi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vccfinv200t57u0jrsiem0qlip