A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism

Serotonin, a central neuromodulator with ancient ties to feeding and metabolism, is a major driver of body fat loss. However, mechanisms by which central serotonin action leads to fat loss remain unknown. Here, we report that the FLP-7 neuropeptide and its cognate receptor, NPR-22, function as the l...

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Detalles Bibliográficos
Autores principales: Palamiuc, Lavinia, Noble, Tallie, Witham, Emily, Ratanpal, Harkaranveer, Vaughan, Megan, Srinivasan, Supriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290170/
https://www.ncbi.nlm.nih.gov/pubmed/28128367
http://dx.doi.org/10.1038/ncomms14237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290170/
https://www.ncbi.nlm.nih.gov/pubmed/28128367
http://dx.doi.org/10.1038/ncomms14237

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