Cargando…

A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance

Damaged mitochondria pose a lethal threat to cells that necessitates their prompt removal. The currently recognized mechanism for disposal of mitochondria is autophagy, where damaged organelles are marked for disposal via ubiquitylation by Parkin. Here we report a novel pathway for mitochondrial eli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hammerling, Babette C., Najor, Rita H., Cortez, Melissa Q., Shires, Sarah E., Leon, Leonardo J., Gonzalez, Eileen R., Boassa, Daniela, Phan, Sébastien, Thor, Andrea, Jimenez, Rebecca E., Li, Hong, Kitsis, Richard N., Dorn II, Gerald W., Sadoshima, Junichi, Ellisman, Mark H., Gustafsson, Åsa B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290275/ https://www.ncbi.nlm.nih.gov/pubmed/28134239 http://dx.doi.org/10.1038/ncomms14050

Ejemplares similares

Endosomal Rab cycles regulate Parkin-mediated mitophagy
por: Yamano, Koji, et al.
Publicado: (2018)

Nuclear Parkin Activates the ERRα Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia
por: Shires, Sarah E., et al.
Publicado: (2020)

PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
por: Kubli, Dieter A., et al.
Publicado: (2015)

Pannexin2 oligomers localize in the membranes of endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane
por: Boassa, Daniela, et al.
Publicado: (2015)

Editorial: Mitochondrial Dysfunction and Cardiovascular Diseases
por: Sadoshima, Junichi, et al.
Publicado: (2021)

Intrinsic tethering activity of endosomal Rab proteins
por: Lo, Sheng-Ying, et al.
Publicado: (2011)

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7
por: Rojas, Raul, et al.
Publicado: (2008)

FgRab5 and FgRab7 are essential for endosomes biogenesis and non-redundantly recruit the retromer complex to the endosomes in Fusarium graminearum
por: Abubakar, Yakubu Saddeeq, et al.
Publicado: (2021)

Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes
por: Lund, Viktor Karlovich, et al.
Publicado: (2018)

Parkin deficiency results in accumulation of abnormal mitochondria in aging myocytes
por: Kubli, Dieter A., et al.
Publicado: (2013)

Distinct Membrane Domains on Endosomes in the Recycling Pathway Visualized by Multicolor Imaging of Rab4, Rab5, and Rab11
por: Sönnichsen, Birte, et al.
Publicado: (2000)

Vps34 and the Armus/TBC-2 Rab GAPs: Putting the brakes on the endosomal Rab5 and Rab7 GTPases
por: Law, Fiona, et al.
Publicado: (2017)

Roles for the recycling endosome, Rab8, and Rab11 in hantavirus release from epithelial cells
por: Rowe, Regina K., et al.
Publicado: (2008)

TBC-2 Regulates RAB-5/RAB-7-mediated Endosomal Trafficking in Caenorhabditis elegans
por: Chotard, Laëtitia, et al.
Publicado: (2010)

De novo formation of early endosomes during Rab5-to-Rab7a transition
por: Skjeldal, Frode Miltzow, et al.
Publicado: (2021)

Rab35 promotes the recruitment of Rab8, Rab13 and Rab36 to recycling endosomes through MICAL-L1 during neurite outgrowth
por: Kobayashi, Hotaka, et al.
Publicado: (2014)

Rab11 regulates recycling through the pericentriolar recycling endosome
Publicado: (1996)

Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling
por: Wang, Xiaolong, et al.
Publicado: (2020)

A conserved and regulated mechanism drives endosomal Rab transition
por: Langemeyer, Lars, et al.
Publicado: (2020)

Rab7 Associates with Early Endosomes to Mediate Sorting and Transport of Semliki Forest Virus to Late Endosomes
por: Vonderheit, Andreas, et al.
Publicado: (2005)

Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance
por: Lonskaya, Irina, et al.
Publicado: (2013)

Aspergillus RabB(Rab5) Integrates Acquisition of Degradative Identity with the Long Distance Movement of Early Endosomes
por: Abenza, Juan F., et al.
Publicado: (2010)

VipD of Legionella pneumophila Targets Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages
por: Ku, Bonsu, et al.
Publicado: (2012)

Estrogen Plays a Crucial Role in Rab9‐Dependent Mitochondrial Autophagy, Delaying Arterial Senescence
por: Sasaki, Yuichi, et al.
Publicado: (2021)

A Novel Rab9 Effector Required for Endosome-to-TGN Transport
por: Díaz, Elva, et al.
Publicado: (1997)

Integration of two RAB5 groups during endosomal transport in plants
por: Ito, Emi, et al.
Publicado: (2018)

Rab5-mediated endosome formation is regulated at the trans-Golgi network
por: Nagano, Makoto, et al.
Publicado: (2019)

Rab GTPases: The principal players in crafting the regulatory landscape of endosomal trafficking
por: Zhang, Jing, et al.
Publicado: (2022)

Rab11 Regulates the Compartmentalization of Early Endosomes Required for Efficient Transport from Early Endosomes to the Trans-Golgi Network
por: Wilcke, Mona, et al.
Publicado: (2000)

RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
por: Heo, J.-M., et al.
Publicado: (2018)

3D reconstruction of biological structures: automated procedures for alignment and reconstruction of multiple tilt series in electron tomography
por: Phan, Sébastien, et al.
Publicado: (2016)

Anterograde Trafficking of KCa3.1 in Polarized Epithelia Is Rab1- and Rab8-Dependent and Recycling Endosome-Independent
por: Bertuccio, Claudia A., et al.
Publicado: (2014)

Receptor-mediated internalization promotes increased endosome size and number in a RAB4- and RAB5-dependent manner
por: Naslavsky, Naava, et al.
Publicado: (2023)

Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation
por: Borchers, Ann-Christin, et al.
Publicado: (2023)

Adenovirus RIDα regulates endosome maturation by mimicking GTP-Rab7
por: Shah, Ankur H., et al.
Publicado: (2007)

Rab GTPase regulation of retromer-mediated cargo export during endosome maturation
por: Liu, Ting-Ting, et al.
Publicado: (2012)

TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis
por: Yu, Shiyan, et al.
Publicado: (2014)

Rab9A is required for delivery of cargo from recycling endosomes to melanosomes
por: Mahanty, Sarmistha, et al.
Publicado: (2016)

A new Rab7 effector controls phosphoinositide conversion in endosome maturation
por: Casanova, James E., et al.
Publicado: (2017)

Kinesin-2 Controls the Motility of RAB5 Endosomes and Their Association with the Spindle in Mitosis
por: Pupo, Emanuela, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_38itgmb3hfqepab64ls522cvta