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A quantized mechanism for activation of pannexin channels

Pannexin 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for purinergic signalling, which is involved in diverse physiological processes such as apoptosis, inflammation, blood pressure regulation, and cancer progression and metastasis. Here we explore the...

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Detalles Bibliográficos
Autores principales: Chiu, Yu-Hsin, Jin, Xueyao, Medina, Christopher B., Leonhardt, Susan A., Kiessling, Volker, Bennett, Brad C., Shu, Shaofang, Tamm, Lukas K., Yeager, Mark, Ravichandran, Kodi S., Bayliss, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290276/
https://www.ncbi.nlm.nih.gov/pubmed/28134257
http://dx.doi.org/10.1038/ncomms14324