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A quantized mechanism for activation of pannexin channels
Pannexin 1 (PANX1) subunits form oligomeric plasma membrane channels that mediate nucleotide release for purinergic signalling, which is involved in diverse physiological processes such as apoptosis, inflammation, blood pressure regulation, and cancer progression and metastasis. Here we explore the...
Autores principales: | Chiu, Yu-Hsin, Jin, Xueyao, Medina, Christopher B., Leonhardt, Susan A., Kiessling, Volker, Bennett, Brad C., Shu, Shaofang, Tamm, Lukas K., Yeager, Mark, Ravichandran, Kodi S., Bayliss, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290276/ https://www.ncbi.nlm.nih.gov/pubmed/28134257 http://dx.doi.org/10.1038/ncomms14324 |
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