KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling

Ciliary membrane composition is controlled by transition zone (TZ) proteins such as RPGRIP1, RPGRIPL and NPHP4, which are vital for balanced coordination of diverse signalling systems like the Sonic hedgehog (Shh) pathway. Activation of this pathway involves Shh-induced ciliary accumulation of Smoot...

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Detalles Bibliográficos
Autores principales: Schou, Kenneth B., Mogensen, Johanne B., Morthorst, Stine K., Nielsen, Brian S., Aleliunaite, Aiste, Serra-Marques, Andrea, Fürstenberg, Nicoline, Saunier, Sophie, Bizet, Albane A., Veland, Iben R., Akhmanova, Anna, Christensen, Søren T., Pedersen, Lotte B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290278/
https://www.ncbi.nlm.nih.gov/pubmed/28134340
http://dx.doi.org/10.1038/ncomms14177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290278/
https://www.ncbi.nlm.nih.gov/pubmed/28134340
http://dx.doi.org/10.1038/ncomms14177

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