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SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE

Biometrical genetic studies suggest that the personality dimensions, including neuroticism, are moderately heritable (~0.4 to 0.6). Quantitative analyses that aggregate the effects of many common variants have recently further informed genetic research on European samples. However, there has been li...

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Detalles Bibliográficos
Autores principales: Docherty, A R, Moscati, A, Peterson, R, Edwards, A C, Adkins, D E, Bacanu, S A, Bigdeli, T B, Webb, B T, Flint, J, Kendler, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290344/
https://www.ncbi.nlm.nih.gov/pubmed/27779626
http://dx.doi.org/10.1038/tp.2016.177