Cargando…
SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE
Biometrical genetic studies suggest that the personality dimensions, including neuroticism, are moderately heritable (~0.4 to 0.6). Quantitative analyses that aggregate the effects of many common variants have recently further informed genetic research on European samples. However, there has been li...
Autores principales: | Docherty, A R, Moscati, A, Peterson, R, Edwards, A C, Adkins, D E, Bacanu, S A, Bigdeli, T B, Webb, B T, Flint, J, Kendler, K S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290344/ https://www.ncbi.nlm.nih.gov/pubmed/27779626 http://dx.doi.org/10.1038/tp.2016.177 |
Ejemplares similares
-
Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia
por: Ahangari, Mohammad, et al.
Publicado: (2023) -
11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project
por: Cai, Na, et al.
Publicado: (2017) -
Retraction Note: 11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project
por: Cai, Na, et al.
Publicado: (2020) -
Affective wellbeing moderates the association between polygenic risk score for neuroticism and change in neuroticism
por: Bahbouhová, J., et al.
Publicado: (2023) -
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model
por: Holland, Dominic, et al.
Publicado: (2020)