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Endogenous Protein Interactome of Human UDP-Glucuronosyltransferases Exposed by Untargeted Proteomics

The conjugative metabolism mediated by UDP-glucuronosyltransferase enzymes (UGTs) significantly influences the bioavailability and biological responses of endogenous molecule substrates and xenobiotics including drugs. UGTs participate in the regulation of cellular homeostasis by limiting stress ind...

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Detalles Bibliográficos
Autores principales: Rouleau, Michèle, Audet-Delage, Yannick, Desjardins, Sylvie, Rouleau, Mélanie, Girard-Bock, Camille, Guillemette, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290407/
https://www.ncbi.nlm.nih.gov/pubmed/28217095
http://dx.doi.org/10.3389/fphar.2017.00023