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A Novel Enterovirus 71 (EV71) Virulence Determinant: The 69th Residue of 3C Protease Modulates Pathogenicity

Human enterovirus type 71 (EV71), the major causative agent of hand-foot-and-mouth disease, has been known to cause fatal neurological complications. Unfortunately, the reason for neurological complications that have been seen in fatal cases of the disease and the relationship between EV71 virulence...

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Detalles Bibliográficos
Autores principales: Li, Bingqing, Yue, Yingying, Zhang, Yajie, Yuan, Zenglin, Li, Peng, Song, Nannan, Lin, Wei, Liu, Yan, Gu, Lichuan, Meng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290453/
https://www.ncbi.nlm.nih.gov/pubmed/28217559
http://dx.doi.org/10.3389/fcimb.2017.00026