The molecular basis of talin2’s high affinity toward β1-integrin

Talin interacts with β-integrin tails and actin to control integrin activation, thus regulating focal adhesion dynamics and cell migration. There are two talin genes, Tln1 and Tln2, which encode talin1 and talin2, and it is generally believed that talin2 functions redundantly with talin1. However, w...

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Detalles Bibliográficos
Autores principales: Yuan, Yaxia, Li, Liqing, Zhu, Yanyan, Qi, Lei, Azizi, Latifeh, Hytönen, Vesa P., Zhan, Chang-Guo, Huang, Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290461/
https://www.ncbi.nlm.nih.gov/pubmed/28155884
http://dx.doi.org/10.1038/srep41989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290461/
https://www.ncbi.nlm.nih.gov/pubmed/28155884
http://dx.doi.org/10.1038/srep41989

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