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Epigenetic origin of evolutionary novel centromeres

Most evolutionary new centromeres (ENC) are composed of large arrays of satellite DNA and surrounded by segmental duplications. However, the hypothesis is that ENCs are seeded in an anonymous sequence and only over time have acquired the complexity of “normal” centromeres. Up to now evidence to test...

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Detalles Bibliográficos
Autores principales: Tolomeo, Doron, Capozzi, Oronzo, Stanyon, Roscoe R., Archidiacono, Nicoletta, D’Addabbo, Pietro, Catacchio, Claudia R., Purgato, Stefania, Perini, Giovanni, Schempp, Werner, Huddleston, John, Malig, Maika, Eichler, Evan E., Rocchi, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290474/
https://www.ncbi.nlm.nih.gov/pubmed/28155877
http://dx.doi.org/10.1038/srep41980