Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

The salt-inducible kinases (SIKs) control a novel molecular switch regulating macrophage polarization. Pharmacological inhibition of the SIKs induces a macrophage phenotype characterized by the secretion of high levels of anti-inflammatory cytokines, including interleukin (IL)-10, and the secretion...

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Detalles Bibliográficos
Autores principales: Darling, Nicola J., Toth, Rachel, Arthur, J. Simon C., Clark, Kristopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290485/
https://www.ncbi.nlm.nih.gov/pubmed/27920213
http://dx.doi.org/10.1042/BCJ20160646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290485/
https://www.ncbi.nlm.nih.gov/pubmed/27920213
http://dx.doi.org/10.1042/BCJ20160646

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