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Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages
The salt-inducible kinases (SIKs) control a novel molecular switch regulating macrophage polarization. Pharmacological inhibition of the SIKs induces a macrophage phenotype characterized by the secretion of high levels of anti-inflammatory cytokines, including interleukin (IL)-10, and the secretion...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290485/ https://www.ncbi.nlm.nih.gov/pubmed/27920213 http://dx.doi.org/10.1042/BCJ20160646 |