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Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria

The influence of parasite genetic factors on immune responses and development of severe pathology of malaria is largely unknown. In this study, we performed genome-wide transcriptomic profiling of mouse whole blood during blood-stage infections of two strains of the rodent malaria parasite Plasmodiu...

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Detalles Bibliográficos
Autores principales: Lin, Jing-wen, Sodenkamp, Jan, Cunningham, Deirdre, Deroost, Katrien, Tshitenge, Tshibuayi Christine, McLaughlin, Sarah, Lamb, Tracey J., Spencer-Dene, Bradley, Hosking, Caroline, Ramesar, Jai, Janse, Chris J., Graham, Christine, O’Garra, Anne, Langhorne, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290525/
https://www.ncbi.nlm.nih.gov/pubmed/28155887
http://dx.doi.org/10.1038/srep41722