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A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerative medicine. Reprogramming is a stepwise process with well-defined stages of initiation, maturation and stabilisation which are critically dependent on interactions between key pluripotency...

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Detalles Bibliográficos
Autores principales: Neganova, Irina, Chichagova, Valeria, Armstrong, Lyle, Lako, Majlinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290526/
https://www.ncbi.nlm.nih.gov/pubmed/28155868
http://dx.doi.org/10.1038/srep41693