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Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1

Chromosome rearrangement is clinically and physiologically important because it can produce oncogenic fusion genes. Chromosome rearrangement requires DNA double-strand breaks (DSBs) at two genomic locations and misrejoining between the DSBs. Before DSB misrejoining, two DSB-containing chromatin regi...

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Detalles Bibliográficos
Autores principales: Yamauchi, Motohiro, Shibata, Atsushi, Suzuki, Keiji, Suzuki, Masatoshi, Niimi, Atsuko, Kondo, Hisayoshi, Miura, Miwa, Hirakawa, Miyako, Tsujita, Keiko, Yamashita, Shunichi, Matsuda, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290537/
https://www.ncbi.nlm.nih.gov/pubmed/28155885
http://dx.doi.org/10.1038/srep41812