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Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. AML is a heterogeneous malignancy characterized by distinct genetic and epigenetic abnormalities. Recent genome-wide DNA methylation studies have highlighted an important role of dysregulated methylation signature in A...

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Detalles Bibliográficos
Autores principales: Li, Yan, Xu, Qingyu, Lv, Na, Wang, Lili, Zhao, Hongmei, Wang, Xiuli, Guo, Jing, Chen, Chongjian, Li, Yonghui, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290606/
https://www.ncbi.nlm.nih.gov/pubmed/28153026
http://dx.doi.org/10.1186/s13045-017-0409-z