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An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs
BACKGROUND: Population based epigenetic association studies of disease and exposures are becoming more common with the availability of economical genome-wide technologies for interrogation of the methylome, such as the Illumina 450K Human Methylation Array (450K). Often, the expected small number of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290610/ https://www.ncbi.nlm.nih.gov/pubmed/28184257 http://dx.doi.org/10.1186/s13148-017-0320-z |